GENOTYPE-GUIDED P2Y12 INHIBITION FOLLOWING PCI BENEFITS CYP2C19 LOSS OF FUNCTION PATIENTS WITH NORMAL RENAL FUNCTION COMPARED TO THOSE WITH CHRONIC KIDNEY DISEASE

the impact of human recombinant erythropoietin on renal function in patients with chronic kidney disease

Loading and maintenance doses of digoxin in patients with normal renal function and those with severely impaired renal function.

T HE clinician may find the equations and terminology in this report confusing and difficult to follow. However, pharinacokinetic theory is of little use unless those familiar with the theory show how application of the theory is of practical importance. This paper is an attempt to do so with a drug that has presented many problems with respect to dosing and toxicity. It is really not important...

Renal function, calcium regulation, and time to hospitalization of patients with chronic kidney disease

BACKGROUND Chronic kidney disease is associated with disruption of the endocrine system that distorts the balance between calcitriol, calcium, phosphate and parathyroid hormone in the calcium regulation system. This can lead to calcification of the arterial tree and increased risk of cardiovascular disease and death. In this study we develop a health metric, based on biomarkers involved in the ...

Renal function trajectory is more important than chronic kidney disease stage for managing patients with chronic kidney disease.

Management of patients with chronic kidney disease (CKD) emphasizes a current level of function as calculated from the modification of diet in renal disease glomerulofiltration rate equations (eGFR) and proteinuria for staging of CKD. Change in a patient's eGFR over time (renal function trajectory) is an additional and potentially more important consideration in deciding which patients will pro...

Cochlear function in patients with chronic kidney disease.

OBJECTIVE To evaluate cochlear functioning in patients (18-45 years old) with varying stages of chronic kidney disease (CKD). Using purposive sampling, 50 participants, 10 in each of the 5 stages of CKD, were selected and underwent pure tone audiometric testing and distortion product otoacoustic emissions (DPOAEs). RESULTS Significant differences (p < 0.05) were found between pure tone audiom...